Is walking backwards, also known as retro walking, a fitness trend you should be trying — assuming you’re willing to get a few quizzical looks from friends and neighbors?

Axsome’s expectation that AXS-05 can win market share from Rexulti is partly built on the belief that the drug candidate has a differentiated safety profile. Rexulti has a boxed warning because of an increased risk of death. There were no deaths in the AXS-05 trials. Jeffrey Cummings, a research professor at the University of Nevada, Las Vegas, discussed what may happen if AXS-05 avoids a boxed warning.

Axsome Therapeutics said on Monday it would seek marketing approval next year for its oral drug to treat agitation in patients with Alzheimer’s disease, after it succeeded in three out of four late-stage studies.

Today, Axsome will host a conference call and webcast to discuss these topline results. Dr. Jeffrey Cummings, Vice Chair of Research at UNLV Department of Brain Health, will join the call and be available for questions.

Walking is one of the simplest and most accessible physical activities, but what happens when the movement is reversed? Backward walking, or retro walking, is a practice that is establishing itself in the world of fitness thanks to its unique benefits. Although it may seem like a modern trend, this technique has ancient origins: it was in fact used in Chinese medicine to improve body balance.

Cleveland Clinic Genome Center researchers have unraveled how microglia, which perform key neuroprotective activities, also can transform and drive harmful processes such as inflammation in Alzheimer’s disease.