Accomplishments: Department of Brain Health

May 10, 2022
Dr. Jeffrey Cummings (Brain Health) released the fifth annual Alzheimer’s Disease Drug Development Pipeline: 2022 publication. The paper reviews the current pipeline of drugs in clinical trials for the treatment of Alzheimer's disease (AD). It examines an updated view of clinical trials, new drugs, and offers a future outlook on drug development…
October 14, 2021
Kristine Bragg, Gwen Marchand, Jonathan Hilpert (all Educational Psychology and Higher Education), and Jeffrey Cummings (Brain Health) recently published the manuscript, "Using Bibliometrics to Evaluate Outcomes and Influence of Translational Biomedical Research Centers" in the Journal of Clinical and Translational Science.
September 8, 2021
Ryan Wirt, Lauren Crew Andrew Ortiz, and Emmanuel Flores (all Neuroscience), Jefferson Kinney (Brain Health), and James Hyman (Psychology) published an article in Communications Biology entitled "Altered theta rhythm and hippocampal-cortical interactions underlie working memory deficits in a hyperglycemia risk factor model of Alzheimer’s disease…
August 13, 2021
Samantha John (DBrain Health) and colleagues published an investigation of two novel smartphone applications that were developed to assess cognitive functioning, "Examination of the reliability and feasibility of two smartphone applications to assess executive functioning in racially diverse older adults." The manuscript, published in the journal …
July 29, 2021
Dr. Jeff Cummings (Brain Health) published "Trial of Pimavanserin in Dementia-Related Psychosis" in the New England Journal of Medicine.       
July 19, 2021
Jeffrey Cummings (Brain Health) co-authored a paper published in Nature on developing the ATX(N) classification, a system for recognizing biomarkers in blood that indicate the presence in the brain of plaques and tangles characteristic of Alzheimer’s disease.  ATX(N) advances allow researchers to diagnose Alzheimer’s disease without…
April 26, 2021
Arpita Basu (Kinesiology and Nutrition Sciences); Kenneth Izuora (Medicine); Jefferson Kinney, Arnold Salazar (both Brain Health); and Jeffrey Ebersole (Dental) published a randomized double-blind controlled trial in Nutrients on the effects of strawberry antioxidant supplementation in adults with the metabolic syndrome. The results revealed…
November 23, 2020
Arnold M. Salazar, Amanda M. Leisgang, Andrew A. Ortiz, and Jefferson W. Kinney (all Brain Health) published a paper titled, “Alterations of GABA B Receptors in the APP/PS1 Mouse Model of Alzheimer’s Disease” in the journal of Neurobiology of Aging. The paper describes the changes occurring in an Amyloid Beta mouse model of Alzheimer's disease …
October 8, 2020
Jefferson Kinney (Brain Health) and James Hyman (Psychology) received a $1.2 million grant from the National Institutes of Aging to continue the research examining the link between Type II diabetes and Alzheimer’s disease. The grant will support them as they continue to investigate the mechanisms underlying Type II diabetes…
June 19, 2020
Dr. Jeffrey Cummings (Brain Health) recently published an article outlining a novel method for determining whether Alzheimer’s drug treatments in clinical trials are ready to move on to the next phase. The paper, “Translational Scoring of Candidate Treatments for Alzheimer’s Disease: A Systematic Approach,” was published in The Journal of Dementia…
May 11, 2020
Dr. Jeffrey Cummings (Brain Health) recently published an article, “The Role of Clinical Trials in Preclinical Alzheimer’s Disease Drug Development Programs," in the Journal of Prevention of Alzheimer’s Disease. The somewhat provocative findings note that despite the trend toward prevention trials becoming more likely (in part because trials in…
April 29, 2020
Dr. Jeffery Cummings (Brain Health) and other members of a joint European Union/United States Task Force recently published, “Non-Amyloid Approaches to Disease Modification for Alzheimer’s Disease” in the Journal of Prevention of Alzheimer’s Disease. In recognition of the complexity of the disease, the task force acknowledges it may require…