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Chambers-Grundy Center for Transformative Neuroscience News

The Chambers-Grundy Center for Transformative Neuroscience provides an academic platform for research and learning opportunities regarding the study of drug development for Alzheimer's disease and other brain disorders. It includes a clinical trials observatory for tracking new treatments, trial designs, and biomarkers in clinical trials for neurodegenerative disorders.

Current Transformative Neuroscience News

test tubes in a laboratory
Research |

Tenth annual report led by noted clinician-scientist Dr. Jeffrey Cummings tracks status, trends associated with 192 active clinical trials worldwide.

slice of brain sitting on desk in lab
Campus News |

The first Neuroscience Research Showcase brings together experts across disciplines to share their work and spark new collaborations.

test tube and pipettes on black table
Research |

Entities sign Memorandum of Understanding to cultivate best-in-class clinical research services for Alzheimer’s and other neurodegenerative diseases.

diagnostic tools and research paper on black table
Campus News |

First-of-its-kind database, supported by Alzheimer's Drug Discovery Foundation, will provide greater access to key data on Alzheimer’s to researchers around the world.

a gloved hand uses a baster to inject a liquid substance into a test tube
Research |

Alzheimer’s treatment studies offer hope as UNLV expert predicts new potential drugs, biomarkers will yield critical insight for future development.

woman in white labcoat using computer
UNLV History |

Amanda Osse is the first recipient of the award named in honor of Nathan Lindsay, who passed away after a 15-year battle with Alzheimer's disease.

Transformative Neuroscience In The News

Vegas Business

Several local and regional startups were showcased recently at UNLV Innovation Day, where Dr. Jeffrey Cummings, director of the Chambers-Grundy Center for Transformative Neuroscience in the Department of Brain Health at the Kirk Kerkorian School of Medicine at UNLV, was excited about the growth of the life sciences ecosystem.

Medical Laboratory Observer

While Alzheimer’s remains a complex disease, recent clinical trials and research efforts have expanded, emphasizing biomarkers and better patient targeting to improve drug development success rates.

Female First

Delayed and imprecise Alzheimer’s diagnoses in the UK are limiting patient access to clinical trials despite rapid growth in experimental treatments.

KNPR News

The number of national clinical trials for Alzheimer’s therapies has increased by 40 percent in the last decade. That’s according to UNLV brain health researcher Jeffrey Cummings’ 10th annual report, published Tuesday in the Alzheimer’s Association’s research journal.

Guardian

Dr Jeffrey Cummings, of the University of Nevada, Las Vegas, has published an annual review of clinical trials for Alzheimer’s drugs for the past decade. The latest review, published in Alzheimer’s & Dementia: Translational Research & Clinical Interventions, reveals a shifting approach to the disease, with fewer drugs designed to remove amyloid and more targeting tau, inflammation and other immune system pathways.

Alzheimer's Research UK

Every year, world‑leading dementia researcher Dr Jeffrey Cummings releases a global snapshot of Alzheimer’s trials – and the 2026 update has just been published. Right now, researchers are evaluating 158 medicines across 192 trials – marking an impressive 40% rise over the past decade. This year’s review also shows the most diverse Alzheimer’s drug pipeline to date.

Transformative Neuroscience Experts

An expert in behavioral neuroscience with concentrations in Alzheimer's disease and schizophrenia.
A renowned expert on Alzheimer's Disease and other neurodegenerative disorders. 

Recent Transformative Neuroscience Accomplishments

Dr. Jeffrey Cummings (Integrated Health Sciences), research professor in the Department of Brain Health and director of the Chambers-Grundy Center for Transformative Neuroscience, will serve as a keynote speaker during the Clinical Trials in Alzheimer's Disease conference in Boston, Massachusetts, on Oct. 24. Cummings has also been a co-…
Research professor and director Jeffrey Cummings, (Brain Health, Chambers-Grundy Center for Transformative Neuroscience) and director Jamie Schwartz (Industry and Business Engagement, Economic Development) were awarded a $1.5 million INNOVATOR grant from the National Institute of Aging (NIA). This five-year grant will help the…
Dr. Jeff Cummings (Brain Health) published "Trial of Pimavanserin in Dementia-Related Psychosis" in the New England Journal of Medicine.       
Jeffrey Cummings (Brain Health) co-authored a paper published in Nature on developing the ATX(N) classification, a system for recognizing biomarkers in blood that indicate the presence in the brain of plaques and tangles characteristic of Alzheimer’s disease.  ATX(N) advances allow researchers to diagnose Alzheimer’s disease without…
Dr. Jeffrey Cummings (Brain Health) recently published an article outlining a novel method for determining whether Alzheimer’s drug treatments in clinical trials are ready to move on to the next phase. The paper, “Translational Scoring of Candidate Treatments for Alzheimer’s Disease: A Systematic Approach,” was published in The Journal of…
Dr. Jeffrey Cummings (Brain Health) recently published an article, “The Role of Clinical Trials in Preclinical Alzheimer’s Disease Drug Development Programs," in the Journal of Prevention of Alzheimer’s Disease. The somewhat provocative findings note that despite the trend toward prevention trials becoming more likely (in part because trials…