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Chambers-Grundy Center for Transformative Neuroscience News

The Chambers-Grundy Center for Transformative Neuroscience provides an academic platform for research and learning opportunities regarding the study of drug development for Alzheimer's disease and other brain disorders. It includes a clinical trials observatory for tracking new treatments, trial designs, and biomarkers in clinical trials for neurodegenerative disorders.

Current Transformative Neuroscience News

a gloved hand uses a baster to inject a liquid substance into a test tube
Research |

Alzheimer’s treatment studies offer hope as UNLV expert predicts new potential drugs, biomarkers will yield critical insight for future development.

woman in white labcoat using computer
UNLV History |

Amanda Osse is the first recipient of the award named in honor of Nathan Lindsay, who passed away after a 15-year battle with Alzheimer's disease.

Students at Pida Plaza on the first day of classes (Josh Hawkins, UNLV).
Campus News |

A roundup of prominent news stories highlighting university pride, research, and community collaboration.

Closeup of a hand holding a model brain
Research |

Annual review of current Alzheimer’s clinical trials reveals trends in design, therapies, outcomes, and funding surrounding work to develop new treatments.
 

Dancers with the U.N.L.V. Ewalu Club
Campus News |

A collection of news stories highlighting research wins, expert insights, and academic achievement.

detail shot of lab equipment
Campus News |

UNLV expert Dr. Jeffrey Cummings explains how a new lab expands UNLV's neuroscience research capabilities.

Transformative Neuroscience In The News

Chic Compass

Alzheimer’s patients and their loved ones have a renewed sense of hope now that the U.S. Food & Drug Administration approved the first Alzheimer’s drug in nearly two decades.

Chic Compass

Alzheimer’s patients and their loved ones have a renewed sense of hope now that the U.S. Food & Drug Administration approved the first Alzheimer’s drug in nearly two decades.

Pedfire

Researchers identified sildenafil, known commercially as Viagra, as a promising candidate for treating Alzheimer’s disease. Leveraging artificial intelligence the team analyzed vast amounts of data, including insurance claims and brain cell observations, to highlight sildenafil’s potential benefits in reducing Alzheimer’s prevalence and neurotoxic proteins.

MedPage Today

Most ARIA cases are mild, but some have been fatal

MedPage Today

Recently approved disease-modifying treatments for Alzheimer's disease have created a sudden demand, but these and other drugs in the pipeline are not for all patients with clinical Alzheimer's symptoms, experts said.

MedPage Today

Looking ahead to 2024 and beyond: "There is so much more to be done"

Transformative Neuroscience Experts

A renowned expert on Alzheimer's Disease and other neurodegenerative disorders. 
An expert in behavioral neuroscience with concentrations in Alzheimer's disease and schizophrenia.

Recent Transformative Neuroscience Accomplishments

Dr. Jeffrey Cummings (Integrated Health Sciences), research professor in the Department of Brain Health and director of the Chambers-Grundy Center for Transformative Neuroscience, will serve as a keynote speaker during the Clinical Trials in Alzheimer's Disease conference in Boston, Massachusetts, on Oct. 24. Cummings has also been a co-…
Research professor and director Jeffrey Cummings, (Brain Health, Chambers-Grundy Center for Transformative Neuroscience) and director Jamie Schwartz (Industry and Business Engagement, Economic Development) were awarded a $1.5 million INNOVATOR grant from the National Institute of Aging (NIA). This five-year grant will help the…
Dr. Jeff Cummings (Brain Health) published "Trial of Pimavanserin in Dementia-Related Psychosis" in the New England Journal of Medicine.       
Jeffrey Cummings (Brain Health) co-authored a paper published in Nature on developing the ATX(N) classification, a system for recognizing biomarkers in blood that indicate the presence in the brain of plaques and tangles characteristic of Alzheimer’s disease.  ATX(N) advances allow researchers to diagnose Alzheimer’s disease without…
Dr. Jeffrey Cummings (Brain Health) recently published an article outlining a novel method for determining whether Alzheimer’s drug treatments in clinical trials are ready to move on to the next phase. The paper, “Translational Scoring of Candidate Treatments for Alzheimer’s Disease: A Systematic Approach,” was published in The Journal of…
Dr. Jeffrey Cummings (Brain Health) recently published an article, “The Role of Clinical Trials in Preclinical Alzheimer’s Disease Drug Development Programs," in the Journal of Prevention of Alzheimer’s Disease. The somewhat provocative findings note that despite the trend toward prevention trials becoming more likely (in part because trials…