Accomplishments: Chambers-Grundy Center for Transformative Neuroscience

July 29, 2021
Dr. Jeff Cummings (Brain Health) published "Trial of Pimavanserin in Dementia-Related Psychosis" in the New England Journal of Medicine.       
July 19, 2021
Jeffrey Cummings (Brain Health) co-authored a paper published in Nature on developing the ATX(N) classification, a system for recognizing biomarkers in blood that indicate the presence in the brain of plaques and tangles characteristic of Alzheimer’s disease.  ATX(N) advances allow researchers to diagnose Alzheimer’s disease without…
June 19, 2020
Dr. Jeffrey Cummings (Brain Health) recently published an article outlining a novel method for determining whether Alzheimer’s drug treatments in clinical trials are ready to move on to the next phase. The paper, “Translational Scoring of Candidate Treatments for Alzheimer’s Disease: A Systematic Approach,” was published in The Journal of Dementia…
May 11, 2020
Dr. Jeffrey Cummings (Brain Health) recently published an article, “The Role of Clinical Trials in Preclinical Alzheimer’s Disease Drug Development Programs," in the Journal of Prevention of Alzheimer’s Disease. The somewhat provocative findings note that despite the trend toward prevention trials becoming more likely (in part because trials in…
April 29, 2020
Dr. Jeffery Cummings (Brain Health) and other members of a joint European Union/United States Task Force recently published, “Non-Amyloid Approaches to Disease Modification for Alzheimer’s Disease” in the Journal of Prevention of Alzheimer’s Disease. In recognition of the complexity of the disease, the task force acknowledges it may require…
April 10, 2020
Dr. Jeffrey Cummings (Brain Health), recently published an article, “An Actigraphy-Based Validation Study of the Sleep Disorder Inventory (SDI) in the Nursing Home" in Frontiers in Psychiatry. It studied the use of the SDI to identify disrupted sleep in dementia patients in nursing homes, which was proven to be useful when done properly…
April 7, 2020
Dr. Jeffery Cummings (Brain Health) and other members of a joint European Union/United States Task Force recently published, “The Future of Anti-Amyloid Trials,” in the Journal of Prevention and Alzheimer’s Disease. The authors analyze the impact of multiple clinical trials that recently ended for a variety of reasons on the Alzheimer's disease…
February 11, 2020
Dr. Jeffrey Cummings (Brain Health) recently published an article, “The Neuropsychiatric Inventory (NPI): Development and Applications,” in the Journal of Geriatric Psychiatry and Neurology. The article reviews the development of the NPI assessment tool since Dr. Cummings first introduced it 25 years ago and which has been used in approximately…
April 23, 2019
Dr. Jeffrey Cummings (Brain Health) co-authored “Anti-Tau Trials for Alzheimer’s Disease: A Report from the EU/US/CTAD Task Force,” which explored incorporating tau biomarkers in clinical trials to provide additional knowledge about the potential for treating Alzheimer’s Disease by targeting tau. This represents a new direction in Alzheimer’s…