Hong Sun (Chemistry and Biochemistry) and her laboratory's research were featured in the most recent issue of Research Features for their model on target acid sphingomyelinase (ASM) for anti-cancer therapy. Titled, "Acid Sphingomyelinase – A Novel Target for Anti-Cancer and Degenerative Diseases?," their research explores how ASM interacts with key components of the plasma membrane of the cell, thereby influencing cell signaling. Her team has discovered that mutations or abnormal expression in the gene that encodes ASM can result in a wide range of impacts, from regulating lifespan to enhancing the risk of cancer and neuron degenerative disease.
According to the magazine, "As we enter the new year we look forward to showcasing new research from around the world and learning how researchers are working to make a difference. This issue we pay homage to the scientists behind our ever-increasing quality of life as we feature the latest in health research. Whether it's the technology that allows us to peer deep into the body or medicines that extend the lives of those with chronic diseases, it's easy to see how advances in health and medicine have touched the lives of nearly every person on the planet."
Other laboratories featured included those at Stanford University, University of Chicago, and Brown University.