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Boo Shan Tseng and Sophia Araujo Hernandez

Published: Boo Shan Tseng and Sophia Araujo Hernandez

Apr 17, 2018

Boo Shan Tseng and Sophia Araujo Hernandez (both Life Sciences), as well as collaborators at the University of Washington and the University of Calgary, published a research article, "A Biofilm Matrix-Associated Protease Inhibitor Protects Pseudomonas Aeruginosa from Proteolytic Attack", in the high-impact journal mBio. The work shows that when bacteria grow in communities called biofilms, the material holding the bacteria together retains a specific extracellular protein. This protein protects the biofilm bacteria from a bactericidal enzyme that is commonly produced by the immune system during infection, representing yet another way biofilm bacteria, which are a common cause of chronic and hospital-acquired infections, can increase their tolerance against the immune response. Hernandez is one of Tseng's undergraduate students.