Published: Jeffrey Ebersole

Jeffrey Ebersole (Dental) co-authored two articles that appeared in the October issue of Advances in Experimental Medicine and Biology. The first, “Comparative Analysis of Gene Expression Patterns for Oral Epithelium-Related Functions with Aging,” used a nonhuman primate model to profile the transcriptome and change and tissues health across the lifespan, and produced results that suggests healthy gingival aging has a relatively limited impact on the broader functions of the epithelium and epithelial cells.

The second, “A Potential Role of Phospholipase 2 Group IIA (PLA2-IIA) in P. gingivalis-Induced Oral Dysbiosis,” presents an innovative hypothesis about a potential mechanism involved in P. gingivalis-induced oral dysbiosis and inflammation based on previous observations and a robust body of literature that supports the antimicrobial and proinflammatory properties of PLA2-IIA, as well as its role in other chronic inflammatory diseases.

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