Submit Materials to the IRB

An eligible principal investigator must be the official researcher of record on all UNLV human subjects protocols. Please review the PI Eligibility Policy to determine who may serve in this role. Students may not serve in the role of PI on a research project; however, they may submit protocols as student investigators working under a faculty member who serves as the PI on the study.

Researchers may submit a study proposal through the IRBNet online submission system. Basic steps for registering a new user account are below. All proposal packages must be signed by the PI listed on the protocol in order to be accepted for review. For additional assistance on submitting a proposal package, contact the Office of Research Integrity – Human Subjects at 702-895-2794 or

IRBNet New User Registration

  1. Under the login box, select “New User Registration”
  2. Complete all required fields, click Continue.
  3. Read the Terms of Use, click Continue.
  4. Type “Las Vegas” into the search bar, click Search, select “University of Nevada, Las Vegas (UNLV)” from the list, click Continue.
  5. Enter your UNLV contact information, click Continue.
  6. Verify the information is correct, click Register.
  7. Read the instructions on how to activate your account, click Continue.
  8. You are returned to the main IRBNet login page.
  9. You must open your email and click on the activation link to activate your account before you login to IRBNet.

What to Submit for IRB Review

Information about the basic materials that make up a study proposal package can be found on our Getting Started page.

Please be advised that all current versions of forms are available for download from within IRBNet. Older versions of forms will no longer be accepted as of July 1, 2015.

Instructional Videos

IRBNet offers two instructional videos to show new users how to work with the system: New Project Submissions and Post‐submission Advanced Topics. These videos can be accessed. If prompted, enter Username (unlv) and Password (training).

View videos

Update a Protocol

  • Modification Request

    Any change to an existing approved protocol must be reviewed and approved by the IRB prior to implementing the change, except when the change is necessary to eliminate apparent immediate hazards to subjects. Modification requests must be submitted through IRBNet online submission system. When making changes to a study that was originally deemed Exempt, send “Project Mail” to ORI-HS after logging in to your IRBNet account to see whether additional review is needed.
  • Continuing Review Request

    The IRB is required to review all non-exempt research projects at intervals appropriate to the degree of risk, but not less than once a year, according to federal regulations. This is called “continuing review.” It is the PI’s responsibility to submit an application for continuing review in sufficient time to permit the IRB to review the application prior to its expiration date. As a service to investigators, the Office of Research Integrity – Human Subjects sends the principal investigator a reminder notification through the IRBNet system 30-60 days prior the study’s expiration date.

Note: No human subjects activity may take place after the expiration date of the protocol.

Continuing review information should be submitted on a Continuing Review Form through IRBNet online submission system. Protocols that do not get renewed through the continuing review process will be closed and archived. Once the Office of Research Integrity – Human Subjects staff closes a study, the only way for the study to resume is for the investigator to submit a new protocol package for review. All human subject interaction must cease until the new application has been approved.