Welcome to Cayuse

Hello Researchers!

UNLV Division of Research and Office of Research Integrity – Human Subjects Unit (ORI-HS) are happy to announce we are updating the human research and IRB submission portal.

Cayuse, the new submission portal boasts many improvements over our existing IRBNet system and we are happy to bring these advancements to you. Cayuse features improvements such as smart online submission forms, embedded help and guidance, improved track changes, dialogue between researchers and reviewers, and more. These features have been designed to improve and streamline the investigator’s experience.

Cayuse is live and available for use as of September 7, 2021. See the below FAQ section to learn how to request your Cayuse login information.

As a result of this new system, ORI-HS will be discontinuing its use of IRBNet effective September 3, 2021. After this date, research requests can only be submitted through Cayuse.

Helpful Information

Cayuse is both more powerful and different from our existing IRBNet system. Live training sessions have now ended. A recorded training session is available to download and view from Google Drive.The Google Drive link can be provided upon request by contacting Cayuse also has a Help Center that offers guidance and walkthroughs on how to navigate the Cayuse system.

If it’s your first time using the Cayuse Help Center, click on the “Sign up” link and enter your name and email address. You will receive an email from Cayuse with a temporary password to access the Cayuse Help Center and from there you can update your password. From the Cayuse Help Center landing page, select “Human Ethics”. Navigate to the desired category for help in a certain area or type a keyword into the search box.

Important Dates

The new Cayuse system will be live on September 7, 2021.

ORI-HS will discontinue its use of the IRBNet system as of September 3, 2021.

IRBNet will cease to be available as of October 8, 2021. Please retrieve all of your study documents prior to this date.


Q: I am a UNLV researcher. How do I get a login for the new Cayuse system?

A: You can request access at any time using the Request for Access to Cayuse Google Form. Access will be granted to you on or after the Cayuse go-live date of September 7, 2021. After this date, you will receive an email notice with your login information. Please note access is granted manually by the ORI-HS team and new requests can take up to two business days to process.

Q: When is the Cayuse training being held? How can I sign up for training?

A: Live training sessions have now ended. A recorded training session is available to download and view from Google Drive. The Google Drive link can be provided upon request by contacting Workshops for colleges and departments can also be scheduled by contacting Dax Miller.

Q: How do I download all my project files from IRBNet to prepare for this transition to Cayuse?

A: In IRBNet, there is no shortcut to download all project documents at once. If you need to download all of a project documents, you may download them individually by navigating to the Designer page, using the blue, downward-facing arrow at the top of the page to open the Package Navigator, selecting All Documents, then downloading each document using the white piece of paper icon. You may wish to click the  "Show All Versions" link if you need to download all versions of each document, rather than just the most recent version of each document. You can also view all project documents from the Submission Detail page by clicking on the All Project Documents; link above the "New and Revised Documents in this Package" table. Again, you may wish to toggle to the "Show All Versions" view, depending on which versions you'd like to download.

Forms and Templates

The forms and templates that you may need for your IRB submission can be currently accessed from Google Drive. The Google Drive link can be found in the Cayuse new study submission form or provided upon request by contacting

The forms and templates cannot be edited directly in Google Drive. To use, open the desired document, select File, then Download as a Microsoft Word (.docx) file. 

The forms and templates will soon be available for download below.


Letters of Support


Study Personnel

Transcribing and Translation