Phagoctosis, Retinal Cell Biology, Retinal Degenerative Diseases (Retinitis pigmentosa and Age-related Macular Degeneration), Obesity, Molecular and Cell Biology, Functional Proteomics by Phage Display
My current research focuses on two areas of diseases: retinal degeneration and obesity. For retinal degeneration, I study the role of retinal pigment epithelium (RPE) cell phagocytosis in photoreceptor death that leads to retinal dysfunction. For obesity, I explore the physiological and pathological roles of tubby in the development of obesity. I use multidisciplinary approaches that include animal models, molecular, cellular, genetic, biochemical and functional proteomics by phage display in combination with next generation DNA sequencing (NGS) technology to investigate the above diseases.