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dental medicine Accomplishments

Feb 9, 2018
Edward Lynch (Dental) and co-workers have had another novel paper published in February 2018 in the prestigious journal Scientific Reports, Nature. The title is Randomized Controlled Clinical Trial on Bleaching Sensitivity and Whitening Efficacy of Hydrogen Peroxide versus Combinations of Hydrogen Peroxide and Ozone. This research assessed the clinical efficacy regarding bleaching sensitivity and tooth shade lightening using a standard hydrogen peroxide (H2O2) bleaching gel compared with the additional use of ozone either before or after application of H2O2. In Group 1, upper anterior teeth were bleached using ozone (produced via a healOzone X4 device) for 60 seconds, then 38 percent H2O2 for 20 minutes. In Group 2, 38 percent H2O2 application (20 min) was followed by ozone (60 s); and air produced by the healOzone machine (60 s) followed by 38 percent H2O2 (20 min) was used in Group 3 (control). Bleaching sensitivity was evaluated via visual analogue scales, and a treatment-blinded reader objectively recorded tooth shades using a colorimeter before and 24 hours after bleaching (at α = 0.05). The H2O2/ozone combination did not result in pain sensations, while both ozone/H2O2 and H2O2 alone increased bleaching sensitivity (p < 0.001). Teeth achieved lighter shades (higher L*/lower b* values) after bleaching in all groups (p < 0.001), while Ozone boosted lighter tooth shades, irrespective of its use before or after H2O2 (p < 0.05). Due to the complimentary effects, applying ozone after H2O2 seems preferable for bleaching. The results of this study should be associated with a major change in how doctors and dentists around the world carry out tooth whitening and make a considerable impact worldwide. From the present outcome it seems clear that ozone and H2O2 successfully acted in concert to boost tooth shades and reduce tooth sensitivity.      

Feb 8, 2018
Ai-Sun "Kelly" Tseng (Life Sciences) and members of the Tseng laboratory recently published a research article titled "A Model for Investigating Developmental Eye Repair in Xenopus" in the journal Experimental Eye Research. This study showed the unexpected finding that frog embryos can fully regrow their eyes after injury. The authors also identified a method to control eye regrowth. Further studies of this model can lead to new strategies for eye repair and regeneration. This study was performed by UNLV students. Ph.D. student Cindy X. Kha is supported by a Top Tier Doctoral Dissertation Grant. For this work, she also won a first-place award for science poster presentation at the recent GPSA research forum. Philip Son (currently attending the UNLV Dental School) was supported in part by a National Science Foundation EPSCoR undergraduate research fellowship and an AANAPISI undergraduate research fellowship . The Tseng lab seeks to identify the mechanisms that enable animals to regrow organs and tissues with the goal of applying this knowledge toward developing regenerative therapeutics.

Feb 6, 2018
Innovation (Research & Economic Development), the university's research magazine, recently received a Bronze Award of Excellence from District VII of the Council for Advancement and Support of Education (CASE). CASE Awards of Excellence showcase best practices in alumni relations, fundraising, public/government relations, advancement services, special events, and outstanding communications from districts across North America. The team members who produced the award-winning 2017 issue of Innovation are editor-in-chief Raegen Pietrucha; consulting editor Cate Weeks; art director S. A. Lien; photographers Josh Hawkins, R. Marsh Starks, and Aaron Mayes; editorial interns Alexandra Karosas and Rachel Glaze; contributing writers Tony Allen, Marian Alper, Afsha Bawany, Shane Bevell, Vaneh Darakjian, Kevin Dunegan, Caroline Funk, Sara Gorgon, Matt Keleman, Sean Kennedy, Kelly McDonough, Kristen Peterson, Angela Ramsey, Jason Scavone, Chelsea Sendgraff, Stan Smith, and Pashtana Usufzy; and proofreaders Liam Frink, David Hatchett, Zach Miles, Lori Olafson, Robin Toles, and Jill Zimbelman. CASE District VII annually recognizes award winners online and at the annual District VII conference, which will take place in San Francisco in March. UNLV award winners are listed online.

Jan 30, 2018
Wenlian Zhou (Dental), Pearl Kim (Health Care Administration), Jay Shen (Community Health Sciences), Joseph Greenway (Center For Health Information Analysis), and Marcia Ditmyer (Dental) recently published an article, “Preventable Emergency Department Visits for Non-Traumatic Dental Conditions: Trends and Disparities in Nevada, 2009-2015," in the American Journal of Public Health, a top journal in the field of public health.    

Jan 29, 2018
Christina Demopoulos (Dental) leads the Seal Nevada South program for which the School of Dental Medicine has received a $7,500 award from Oral Health America. The program has provided more than 8,500 sealants to 2,500 children since 2010. Many of the children are uninsured and receive free follow-up dental care at the school’s Saturday Morning Children’s Clinic. This is the eighth consecutive year Oral Health America has financially supported the school to provide the sealant program.

Jan 26, 2018
Jeffrey Ebersole (Dental) co-authored “Hypoxia Inducible Transcription Factors, HIF1A and HIF2A, Increase in Aging Mucosal Tissues,” which produced findings that hypoxic stress may exist in aging gingival tissues and may provide an explanatory molecular risk factor for pathogenic microbial challenges. The article appeared in the Jan. 16 issue of Immunology.

Jan 16, 2018
Dr. Jeffrey Ebersole (Dental) co-authored “Patters of Systemic and Cervicovaginal Fluid Inflammatory Cytokines Throughout Pregnancy,” which determined that differences in cytokine distribution across different biological fluids are evident throughout pregnancy. The findings provide a framework for examining patterns of changes in cytokines throughout pregnancy. The article appeared in the second issue (2018) of the American Journal of Perinatology.

Jan 12, 2018
Kenneth Izuora (School of Medicine), Ammar Yousif (School of Medicine), Gayle Allenback, Civon Gewelber (School of Dental Medicine) and Michael Neubauer (School of Dental Medicine) presented "Dental Loss Among Hospitalized Patients with and without Diabetes" at the American Public Health Association Annual Meeting and Expo held in Atlanta.  This poster presentation included results of an investigator initiated study designed to understand the clinical outcomes associated with dental loss among hospitalized patients with and without diabetes.  

Dec 18, 2017
Dr. Karl Kingsley and Amy Tam (both Dental) published the research article "Microbial Ecology of Scardovia Wiggsiae-Positive and Negative Samples" in the Journal of Scientific Discovery in October.

Dec 18, 2017
Dr. Antonina Capurro, Dr. Elana Farfel, and Edward Lynch (all Dental) earned honors from the International Academy for Dental Facial Esthetics during the Greater New York Dental meeting. Capurro and Farfel graduated as academy fellows, and Lynch — also a fellow — received an award for Outstanding Research and Education in the Field of Dental Facial Esthetics. Lynch also was reappointed as international regent for the Academy for Dental Facial Esthetics. The academy is an honorary service organization dedicated to fostering interdisciplinary education and research in the area of facial esthetics.