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Chemistry Seminar: Hua Guo

When

Apr. 4, 2014, 2:30pm to 3:30pm

Campus Location

Office/Remote Location

Room 101

Description

Professor Hua Guo from the department of chemistry and chemical biology at the University of New Mexico will be the featured speaker at a department of chemistry seminar. His talk is titled, "Do X-ray structures of enzymes tell us about catalytic mechanisms? - What we learned from studying bacterial enzymes conferring antibiotic resistance."

Bacterial resistance to antibiotics is a clear and present threat to public health, as illustrated by the recent discovery of the "superbug" NDM-1 that is resistant to almost all antibiotics. The antibiotic resistance is conferred by a class of bacterial enzymes called beta-lactamases. The development of effective inhibitors of such an enzyme requires knowledge of the catalytic mechanism, which is often derived from three-dimensional structures of the enzyme obtained from X-ray diffraction. But do these structures tell us the true story of how the catalysis is performed by the enzyme?

Admission Information

Admission is free. No ticket required.

Contact information

Name: Shane Bevell
Office: Department of Chemistry
Phone: 702-895-3510
E-mail: deborah.masters@unlv.edu

Event Sponsor

Department of Chemistry